Serum retinol binding protein-4 and neutrophil gelatinase-associated lipocalin are interrelated in pancreatic cancer patients

摘要: Objectives. Pancreatic cancer has an extremely dismal clinical course and high fatality rate. Knowing that, adipokines could regulate insulin resistance, inflammation, immunity carcinogenesis. Accordingly, understanding of in relation to pancreatic be useful improve disease outcome. We aimed determine serum retinol binding protein-4 (RBP-4) neutophil gelatinase-associated lipocalin (NGAL) levels patients. Moreover, we assessed their association with tumor severity each other. Methods. A total 23 patients 20 healthy controls were enrolled. Fifteen the underwent Whipple resection examined before after operation. Serum glucose, insulin, lipid profile, CA19-9, RBP-4 NGAL estimated by ELISA. Results. Significant elevation concentrations (64.4 ± 5.6 ng/ml) (142(80–235) at p < 0.001 was found Both RBP-4...