Hepatitis E during Tocilizumab Therapy in a Patient with Rheumatoid Arthritis: Case Report and Literature Review.
作者： Hidekazu Ikeuchi , Kana Koinuma , Masao Nakasatomi , Toru Sakairi , Yoriaki Kaneko
DOI: 10.1155/2018/6873276
关键词:
摘要: Hepatitis E is an acute self-limiting disease caused by hepatitis virus (HEV). Recent reports show that HEV can induce chronic or be reactivated in immunocompromised hosts. We report a 63-year-old woman with rheumatoid arthritis (RA) who developed during treatment tocilizumab. Analysis of serially stocked serum samples confirmed was primary infection and not viral reactivation. Her liver function improved after discontinuing tocilizumab remained within the normal range without reactivation for >5 years restarting also reviewed published cases RA treatment.
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