Development of T cell lineages in rat lacrimal glands
作者： Nancy L. O’Sullivan , Cheryl A. Skandera , Paul C. Montgomery
DOI: 10.1076/CEYR.22.5.375.5497
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摘要: Purpose. The purpose of this study was to examine T cell development in rat lacrimal glands, determine whether the thymus is source immature cells tissue and compare gland lymphocytes with other subpopulations. Methods. Mononuclear were isolated from glands normal or thymectomized female Fischer 344 rats stained for flow cytometric analysis. Results. lymphocyte population included large percentages an activated phenotype also subpopulations immature, naive memory cells. numbers (Thy-1 +) unchanged following short-term adult thymectomy. In comparison, spleen had cells, only a small subpopulation similar which nearly eliminated after Lacrimal TCR?d + CD8aa NKT a...
informahealthcare.com参考文章(34)
Nancy L. O’Sullivan, Cheryl A. Skandera, Paul C. Montgomery, Rat Lacrimal Glands Contain Activated and Resting Mature T Cells, Recent Thymic Emigrants, and Possibly Extrathymic Populations Advances in Experimental Medicine and Biology. ,vol. 438, pp. 591- 598 ,(1998) , 10.1007/978-1-4615-5359-5_83
Uchio E, Ohno S, Yanagita M, Kiyono H, Aoki K, Iijima H, Saitoh-Inagawa W, Hiroi T, Unique Characteristics of Lacrimal Glands as a Part of Mucosal Immune Network: High Frequency of IgA-Committed B-1 Cells and NK1.1+ αβ T Cells Investigative Ophthalmology & Visual Science. ,vol. 41, pp. 138- 144 ,(2000)
F. Powrie, D. Mason, Subsets of Rat CD4+ T Cells Defined by Their Differential Expression of Variants of the CD45 Antigen: Developmental Relationships and In Vitro and In Vivo Functions Immunological Memory. ,vol. 159, pp. 79- 96 ,(1990) , 10.1007/978-3-642-75244-5_5
J. Daniel Nelson, A CLINICIAN LOOKS AT THE TEARFILM Advances in Experimental Medicine and Biology. ,vol. 438, pp. 1- 9 ,(1998) , 10.1007/978-1-4615-5359-5_1
Irving Goldschneider, Lance K. Gordon, Mary A. Ritter, Distribution and Identity of Thy-1-Bearing Cells during Ontogeny in Rat Hemopoietic and Lymphoid Tissues Journal of Immunology. ,vol. 121, pp. 2463- 2471 ,(1978)
H Hosseinzadeh, I Goldschneider, Recent thymic emigrants in the rat express a unique antigenic phenotype and undergo post-thymic maturation in peripheral lymphoid tissues. Journal of Immunology. ,vol. 150, pp. 1670- 1679 ,(1993)
Nancy L. O’Sullivan, Cheryl A. Skandera, Paul C. Montgomery, Lymphocyte Lineages at Mucosal Effector Sites: Rat Salivary Glands Journal of Immunology. ,vol. 166, pp. 5522- 5529 ,(2001) , 10.4049/JIMMUNOL.166.9.5522
J R McGhee, H Kiyono, J Mega, Cytokine- and Ig-producing T cells in mucosal effector tissues: analysis of IL-5- and IFN-gamma-producing T cells, T cell receptor expression, and IgA plasma cells from mouse salivary gland-associated tissues. Journal of Immunology. ,vol. 148, pp. 2030- 2039 ,(1992)
Kazuo Ohtsuka, Tsuneo Iiai, Hisami Watanabe, Toshiyuki Tanaka, Masayuki Miyasaka, Kazunari Sato, Hitoshi Asakura, Toru Abo, Similarities and Differences between Extrathymic T Cells Residing in Mouse Liver and Intestine Cellular Immunology. ,vol. 153, pp. 52- 66 ,(1994) , 10.1006/CIMM.1994.1005
Josef Fangmann, Reinhard Schwinzer, Kurt Wonigeit, Unusual phenotype of intestinal intraepithelial lymphocytes in the rat: predominance of T cell receptor α/β+/CD2− cells and high expression of the RT6 alloantigen European Journal of Immunology. ,vol. 21, pp. 753- 760 ,(1991) , 10.1002/EJI.1830210331