Additive manufacturing in the development of 3D skin tissues

摘要: In the same way that it has transformed production of other solid objects, additive manufacturing power to transform drug discovery and regenerative medicine by enabling creation complex multilayered tissues through an automated platform. The growing number new bioprinted skin models potential better recapitulate native tissue biology with a degree complexity, flexibility, reproducibility not achievable traditional manual fabrication approaches. this review, we provide overview current bioprinting approaches being used today, how they are applied fabricate next generation ex vivo human equivalents for use in toxicology, pharmacological screening, disease modeling, therapeutic applications.