Synthesis, characterization, molecular modeling, and thermal analyses of bioactive Co(II) and Cu(II) complexes with diacetylmonoxime and different amines

摘要: Condensation of diacetylmonoxime with 2-amino-5-mercapto-1,3,4-thiadiazole, 2-amino-1,3,4-thiadiazole or 3-amino-5-methylisoxazole in the presence Co(II) and Cu(II) salts different anions produced nine complexes. The synthesized complexes have been characterized by elemental analyses, molar conductivities, thermal magnetic moments, IR, electron spin resonance, UV-Vis spectral studies. data show that sulfur, oxygen, nitrogen participate chelation metal ions. are tetrahedral, octahedral, square planar based on amine used nature anion. Molar conductance measurements DMF indicate non-electrolytes. CS Chem 3-D Ultra Molecular Modeling Analysis Program has for optimization molecular structures some In vitro cytotoxicities were tested against carcinoma cell lines. Antimicrobial activities screened Gram-positive (Staphylo...