Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion.
作者： K Brand , S Page , G Rogler , A Bartsch , R Brandl
DOI: 10.1172/JCI118598
关键词:
摘要: Nuclear factor-kappa B (NF-kappaB)/Rel transcription factors play an important role in the inducible regulation of a variety of genes involved in the inflammatory and proliferative …
dm5migu4zj3pb.cloudfront.net 参考文章(50)
P A Baeuerle, T Henkel, Function and Activation of NF-kappaB in the Immune System Annual Review of Immunology. ,vol. 12, pp. 141- 179 ,(1994) , 10.1146/ANNUREV.IY.12.040194.001041
N Marui, M K Offermann, R Swerlick, C Kunsch, C A Rosen, M Ahmad, R W Alexander, R M Medford, Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells Journal of Clinical Investigation. ,vol. 92, pp. 1866- 1874 ,(1993) , 10.1172/JCI116778
LG Fong, TA Fong, AD Cooper, Inhibition of lipopolysaccharide-induced interleukin-1 beta mRNA expression in mouse macrophages by oxidized low density lipoprotein. Journal of Lipid Research. ,vol. 32, pp. 1899- 1910 ,(1991) , 10.1016/S0022-2275(20)41893-0
P Libby, G K Hansson, Involvement of the immune system in human atherogenesis: current knowledge and unanswered questions. Laboratory Investigation. ,vol. 64, pp. 5- 15 ,(1991)
Badimon Jj, Chesebro Jh, Fuster, Badimon L, Coronary atherosclerosis : a multifactorial disease Circulation. ,vol. 87, ,(1993)
J L Witztum, D Steinberg, Role of oxidized low density lipoprotein in atherogenesis. Journal of Clinical Investigation. ,vol. 88, pp. 1785- 1792 ,(1991) , 10.1172/JCI115499
Joseph L. Witztum, Seppo Ylä-Herttuala, Michael E. Rosenfeld, Beth A. Lipton, Daniel Steinberg, Virginia A. Ord, Macrophage colony-stimulating factor mRNA and protein in atherosclerotic lesions of rabbits and humans. American Journal of Pathology. ,vol. 140, pp. 291- 300 ,(1992)
A. M. Gown, R. Ross, T. Tsukada, Human atherosclerosis. II. Immunocytochemical analysis of the cellular composition of human atherosclerotic lesions. American Journal of Pathology. ,vol. 125, pp. 191- 207 ,(1986)
Thomas S Edgington, Nigel Mackman, Korbinian Brand, Wolfram Ruf, The structural biology of expression and function of tissue factor. Thrombosis and Haemostasis. ,vol. 66, pp. 67- 79 ,(1991) , 10.1055/S-0038-1646375
Collins T, Endothelial nuclear factor-kappa B and the initiation of the atherosclerotic lesion. Laboratory Investigation. ,vol. 68, pp. 499- 508 ,(1993)