摘要: The evolution of technology and bioinformatics in genomic research over the last 10 years has enabled investigator to include complex molecular analyses clinical trial design explore biological mechanisms behind observations seen with intervention. Whether you incorporate whole genome expression studies, genome-wide screening for polymorphisms, or pharmacogenomics, these methods are now not only feasible, but provide a very powerful translational strategy. Genomic might be primary focus trial, they also fit well modularly as secondary line investigation supporting protocol. Newer technologies like next generation sequencing genetic engineering offer promise rapid throughput, more cost effective, real-time applicability. Using guide patient diagnosis, staging, treatment personalized medicine approach will greatly positively impact outcomes. Collaboration between scientists, biologists, experts provides synergy that drives success comprehensive multidisciplinary program.