Rodent models of experimental autoimmune uveitis.
作者： Rajeev K. Agarwal , Rachel R. Caspi
DOI: 10.1385/1-59259-805-6:395
关键词:
摘要: The model of experimental autoimmune uveitis (EAU) in mice and rats is described. EAU targets immunologically privileged retinal antigens serves as a humans well for autoimmunity more general sense. well-characterized, robust, reproducible that easily followed quantitated. It inducible with synthetic peptides derived from autoantigens commonly available strains mice. ability to induce various gene-manipulated, including HLA-transgenic, mouse makes the suitable study basic mechanisms clinically relevant interventions.
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