Flow cytometric DNA analysis in gynecological oncology.

作者: P.A. van Dam , J.V. Watson , D.G. Lowe , J.H. Shepherd

DOI: 10.1046/J.1525-1438.1992.02020057.X

关键词:

摘要: The relevance of flow cytometric DNA analysis in neoplasia the female genital tract is reviewed. virtues and limitations technique are discussed. There good evidence, mainly from retrospective studies, that ploidy and/or tumor S-phase fraction valuable prognostic indicators patients with carcinoma ovary endometrium. Further prospective studies needed, however, to establish precise value before it can be used safely for stratification therapeutic regimes.

参考文章(51)
G. Valet, M. G. Ormerod, H. H. Warnecke, G. Benker, G. Ruhenstroth-Bauer, Sensitive three-parameter flow-cytometric detection of abnormal cells in human cervical cancers: A pilot study Journal of Cancer Research and Clinical Oncology. ,vol. 102, pp. 177- 184 ,(1981) , 10.1007/BF00410669
Robert P. Wersto, Roberta L. Liblit, Daniel Deitch, Leopold G. Koss, Variability in dna measurements in multiple tumor samples of human colonic carcinoma Cancer. ,vol. 67, pp. 106- 115 ,(1991) , 10.1002/1097-0142(19910101)67:1<106::AID-CNCR2820670120>3.0.CO;2-I
Lars L. Vindeløv, Ib J. Christensen, Niels Keiding, Mogens Spang-Thomsen, Nis I. Nissen, Long-term storage of samples for flow cytometric DNA analysis. Cytometry. ,vol. 3, pp. 317- 322 ,(1983) , 10.1002/CYTO.990030502
J.E.D. Dyson, C.A.F. Joslin, P. Quirke, C.C. Bird, Flow cytofluorometric analysis of serial biopsies of tumours of the uterine cervix European Journal of Cancer and Clinical Oncology. ,vol. 20, pp. 1249- 1259 ,(1984) , 10.1016/0277-5379(84)90255-4
Vanessa M. Barhabei, David Scott Miller, Kenneth D. Bauer, Tariq M. Murad, Alfred W. Rademaker, John R. Lurain, Flow cytometric evaluation of epithelial ovarian cancer American Journal of Obstetrics and Gynecology. ,vol. 162, pp. 1584- 1592 ,(1990) , 10.1016/0002-9378(90)90924-V
Anders Jakobsen, Ploidy level and short-time prognosis of early cervix cancer. Radiotherapy and Oncology. ,vol. 1, pp. 271- 275 ,(1984) , 10.1016/S0167-8140(84)80010-9
P. Strang, A. Lindgren, B. Frankendal, U. Stendahl, Dna Patterns and Aggressive Histopathologic Features in 159 Patients with Cervical Carcinoma International Journal of Gynecological Pathology. ,vol. 7, pp. 56- 63 ,(1988) , 10.1097/00004347-198803000-00006
Anders Jakobsen, Prognostic impact of ploidy level in carcinoma of the cervix. American Journal of Clinical Oncology. ,vol. 7, pp. 475- 480 ,(1984) , 10.1097/00000421-198410000-00016