Drug off-target effects predicted using structural analysis in the context of a metabolic network model.

作者: Roger L. Chang , Li Xie , Lei Xie , Philip E. Bourne , Bernhard Ø. Palsson

DOI: 10.1371/JOURNAL.PCBI.1000938

关键词:

摘要: … -treated model, and are referred to in this study as cryptic genetic risk factors. Five such gene … The concept of cryptic genetic risk factors for drug treatment introduced in this study …

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