Terminal Transferase and Adenosine Deaminase Activities in Human Neoplasia: Their Role in Modulating Cancer Treatment

作者: P. S. Sarin , A. Thornton , D. Sun

DOI: 10.1007/978-1-4684-5242-6_14

关键词:

摘要: Terminal deoxynucleotidyl transferase (TdT) and adenosine deaminase (ADA) are two enzyme markers that have been exstensively utilized to define the stage of disease cell types involved in human leukemia B proliferation severe combined immune deficiency syndrome (SCID). The use these biological has very useful selecting treatment protocols for patients with leukemia/lymphoma SCID.

参考文章(61)
R. McCaffrey, R. Bell, A. Lillquist, G. Wright, E. Baril, J. Minowada, Selective Killing of Leukemia Cells by Inhibition of TdT Haematology and blood transfusion. ,vol. 28, pp. 24- 27 ,(1983) , 10.1007/978-3-642-68761-7_4
Samson T. Jacob, Enzymes of nucleic acid synthesis and modification CRC Press. ,(1983)
F.J. Bollum, Oligodeoxyribonucleotide-primed reactions catalyzed by calf thymus polymerase. Journal of Biological Chemistry. ,vol. 237, pp. 1945- 1949 ,(1962) , 10.1016/S0021-9258(19)73964-7
David Baltimore, Patrick C. Kung, Paul D. Gottlieb, Terminal deoxynucleotidyltransferase. Serological studies and radioimmunoassay. Journal of Biological Chemistry. ,vol. 251, pp. 2399- 2404 ,(1976) , 10.1016/S0021-9258(17)33601-3
Stephen Sallan, Anne Lillquist, Ellen Cohen, Michael Osband, Ronald McCaffrey, Clinical Utility of Leukemia Cell Terminal Transferase Measurements Cancer Research. ,vol. 41, pp. 4814- 4820 ,(1981)
Hitoshi Akedo, Hiromu Nishihara, Kiyoko Shinkai, Keiko Komatsu, Satsuki Ishikawa, Multiple forms of human adenosine deaminase: I. Purification and characterization of two molecular species Biochimica et Biophysica Acta. ,vol. 276, pp. 257- 271 ,(1972) , 10.1016/0005-2744(72)90028-9
Beatrice Lampkin, John J. Hutton, F. J. Bollum, Martha F. Greenwood, Mary Sue Coleman, Phillip Holland, Serial observations on terminal deoxynucleotidyl transferase activity and lymphoblast surface markers in acute lymphoblastic leukemia. Cancer Research. ,vol. 36, pp. 120- 127 ,(1976)
Stephen E. Sallan, David G. Poplack, Richard Ungerleider, Sharon B. Murphy, John Holcenberg, Gaston Rivera, Daniel L. Glaubiger, Julie Blatt, Peter Venner, David Johns, Jeffrey M. Lipton, Phase I Study of 2′-Deoxycoformycin in Acute Lymphoblastic Leukemia Cancer Research. ,vol. 41, pp. 3343- 3346 ,(1981)
W N Kelley, P E Daddona, Human adenosine deaminase. Purification and subunit structure. Journal of Biological Chemistry. ,vol. 252, pp. 110- 115 ,(1977) , 10.1016/S0021-9258(17)32805-3