Allelic frequencies and heterozygosities of microsatellite markers covering the whole genome in the Korean

摘要: Microsatellite markers are an essential tool for genetic linkage analysis because of their high polymorphism content. Four hundred commercially available covering the entire genome were genotyped from 578 sib individuals 249 Korean families. Allelic frequencies and heterozygosities determined each marker loci compared between Korean, Taiwanese, Japanese Caucasian populations. In three Asian populations, 10–13% had less than 0.6 heterozygosity, whereas in population, only 0.5% heterozygosity. Mean identical by descent (IBD) values calculated individuals.Analysis IBD greater 0.5 suggested that with low heterozygosity can also provide positive linkages, at least sharing method model-free analysis. The data presented this study will be a useful reference genome-wide screens Koreans comparative studies other ethnic