Animal models for SARS and MERS coronaviruses.

摘要: The emergence of Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) and Middle East (MERS-CoV), two strains animal coronaviruses that crossed the species barrier to infect cause severe respiratory infections in humans within last 12 years, have taught us represent a global threat does not recognize international borders. We can expect see other novel emerge future. An ideal model should reflect clinical signs, viral replication pathology seen humans. In this review, we present factors consider establishing an for study compare different models been employed SARS-CoV MERS-CoV.