作者: Lore Florin , Hitto Kaufmann , Michaela Strotbek , Angelika Hausser , Monilola Olayioye
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摘要: The invention concerns the field of cell culture technology. It RNA having a specific sequence, expression vectors encoding said RNA, production host lines comprising and methods producing recombinant biopharmaceutical products using engineered with altered levels RNAs, such as small non-coding preferably micro RNAs (mi RNAs). also relates to cells in one or more RNAs. Those have improved secretion and/or growth characteristics comparison control lines.