Incomplete vaccination coverage in European children with end-stage kidney disease prior to renal transplantation

摘要: Because infections constitute a major cause of morbidity and mortality in paediatric renal allograft recipients, avoidance preventable systemic by vaccination before transplantation is utmost importance. However, data on the completeness vaccinations factors associated with incomplete coverage are scarce. Within framework Cooperative European Paediatric Renal Transplant Initiative (CERTAIN), we therefore performed multi-centre, multi-national, retrospective study investigating 254 children end-stage disease (mean age 10.0 ± 5.6 years). Only 22 out patients (8.7%) presented complete coverage. In particular, respective against human papillomavirus (27.3%), pneumococci (42.0%), meningococci (47.9%) was low. Patients pneumococcal had numerically less lower respiratory tract during first 3 years post-transplant than without or an status (16.4% vs 27.7%, p = 0.081). Vaccine-preventable diseases were 4.0 times more frequently unvaccinated vaccinated patients. Factors non-Caucasian ethnicity (OR 9.21, p = 0.004), chronic dialysis treatment 6.18, p = 0.001), older at 1.33, p < 0.001). The kidney transplant candidates incomplete. nephrologists, together primary-care staff patients’ families, should make every effort to improve rates transplantation.