Rapidly Cycling Affective Disorder

摘要: • Of 919 patients with major affective disorders who completed at least 1 year of a 5-year, semiannual followup, 45 developed rapidly cycling bipolar course during the first year, but only one unipolar course. In comparison showed non—rapidly course, those became rapid cyclers were more likely to be female and have exhibited depression, hypomania, or between depression hypomania within index episode. Family study data revealed no evidence that high cycle frequencies breed true. Rapid was associated significantly lower likelihood recovery in second follow-up not third, fourth, fifth. These suggest is, large majority cases, transient, nonfamilial manifestation disorder.