Centrins in unicellular organisms: functional diversity and specialization
作者： Yu Zhang , Cynthia Y. He
DOI: 10.1007/S00709-011-0305-2
关键词:
摘要: Centrins (also known as caltractins) are conserved, EF hand-containing proteins ubiquitously found in eukaryotes. Similar to calmodulins, the calcium-binding hands centrins fold into two structurally similar domains separated by an alpha-helical linker region, shaping like a dumbbell. The small size (15-22 kDa) and domain organization of their functional diversity/specialization make them ideal system study protein structure-function relationship. Here, we review work on with focus structures functions characterized unicellular organisms.
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