Pten is essential for embryonic development and tumour suppression.
作者： Antonio D. Cristofano , Barbara Pesce , Carlos Cordon-Cardo , Pier P. Pandolfi
DOI: 10.1038/1235
关键词:
摘要: … generated ES cells lacking Pten activity to study tumorigenesis by Pten –/– cells. Pten +/– ES … We found that the disruption of Pten function resulted in embryonic lethality, and that Pten …
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