Optical coherence tomography: a novel technique for the study of tissue microcirculation
作者： Junji Seki
DOI: 10.5372/ABM.V1I2.110
关键词:
摘要: Background: Three-dimensional (3D) observation techniques are useful for understanding organ microcirculation. Optical coherence tomography (OCT) is one of the 3-D imaging and increasingly applied tissue microcirculatory studies. Objective: This article reviews current prospective usages OCT in Methods: an optical technique to obtain tomographic images highly scattering media like living tissues by means gating, whose spatial resolution down 10 μm. It also capable obtaining velocity profiles blood flow use Doppler frequency shift (Doppler OCT). Results: The has been microvessels rat skin, hamster dorsal brain etc. Small 20 μm have detected with aid OCT. revealed that a quasi-steady laminar flow. signal from cerebral cortex was found change following neural activation, probably reflecting functional hyperemia. Conclusion: combined great potential vivo structures distribution. Further expected be depth-dependent tool study function.
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