Vertical graphene nanoflakes for the immobilization, electrocatalytic oxidation and quantitative detection of DNA

作者: Naigui Shang , Ajay Kumar , Nijuan Sun , Surbhi Sharma , Pagona Papakonstantinou

DOI: 10.1016/J.ELECOM.2012.09.036

关键词:

摘要: Abstract Vertical graphene nanoflake integrated films having a high density of edge planes have been used as an electrochemical platform to systematically investigate the immobilization, oxidation kinetics and direct quantitative determination native DNA. Consistently, both transmission electron microscopy atomic force observations demonstrate presence self-assembled monolayer DNA, immobilized on nanoflakes. Graphene shows excellent electrocatalytic activity for electrooxidation double stranded better than carbon nanotubes glassy carbon, due abundance edges present not only at top but also along sides each nanoflake.

参考文章(30)
Nai Gui Shang, Pagona Papakonstantinou, Martin McMullan, Ming Chu, Artemis Stamboulis, Alessandro Potenza, Sarnjeet S. Dhesi, Helder Marchetto, Catalyst-Free Efficient Growth, Orientation and Biosensing Properties of Multilayer Graphene Nanoflake Films with Sharp Edge Planes** Advanced Functional Materials. ,vol. 18, pp. 3506- 3514 ,(2008) , 10.1002/ADFM.200800951
Ali Özcan, Yücel Şahin, Mehmet Özsöz, Servet Turan, Electrochemical Oxidation of ds‐DNA on Polypyrrole Nanofiber Modified Pencil Graphite Electrode Electroanalysis. ,vol. 19, pp. 2208- 2216 ,(2007) , 10.1002/ELAN.200703957
T Gregory Drummond, Michael G Hill, Jacqueline K Barton, Electrochemical DNA sensors Nature Biotechnology. ,vol. 21, pp. 1192- 1199 ,(2003) , 10.1038/NBT873
Arzum Erdem, Pagona Papakonstantinou, Hayley Murphy, Direct DNA Hybridization at Disposable Graphite Electrodes Modified with Carbon Nanotubes Analytical Chemistry. ,vol. 78, pp. 6656- 6659 ,(2006) , 10.1021/AC060202Z
Bachir Saoudi, Christelle Despas, Mohamed M. Chehimi, Noraldeen Jammul, Michel Delamar, Jacques Bessière, Alain Walcarius, Study of DNA adsorption on polypyrrole: interest of dielectric monitoring Sensors and Actuators B-chemical. ,vol. 62, pp. 35- 42 ,(2000) , 10.1016/S0925-4005(99)00356-1
Alon A. Gorodetsky, Jacqueline K. Barton, Electrochemistry using self-assembled DNA monolayers on highly oriented pyrolytic graphite. Langmuir. ,vol. 22, pp. 7917- 7922 ,(2006) , 10.1021/LA0611054
Xiaohua Cai, Gustavo Rivas, Percio AM Farias, Haruki Shiraishi, Joseph Wang, Emil Palecek, None, Evaluation of different carbon electrodes for adsorptive stripping analysis of nucleic acids Electroanalysis. ,vol. 8, pp. 753- 758 ,(1996) , 10.1002/ELAN.1140080809
Anna M. Nowicka, Ewelina Zabost, Mikolaj Donten, Zofia Mazerska, Zbigniew Stojek, Electrooxidation of dissolved dsDNA backed by in situ UV–Vis spectroscopy Bioelectrochemistry. ,vol. 70, pp. 440- 445 ,(2007) , 10.1016/J.BIOELECHEM.2006.07.003