Carbon nanotube-based ultrasensitive multiplexing electrochemical immunosensor for cancer biomarkers.
作者： Ying Wan , Wangping Deng , Yan Su , Xinhua Zhu , Cheng Peng
DOI: 10.1016/J.BIOS.2011.08.033
关键词:
摘要: A multiplexing electrochemical immunosensor was developed for ultrasensitive detection of cancer related protein biomarkers. We employed disposable screen-printed carbon electrode (SPCE) array as the platform. universal multi-labeled nanoprobe by loading HRP and goat-anti-rabbit IgG (secondary antibody, Ab(2)) onto multiwalled nanotube (MWNT). This available virtually any sandwich-based antigen showed superiority in several areas. By using SPCE nanoprobe, we could detect low 5 pg mL(-1) prostate specific (PSA) 8 Interleukin (IL-8) with immunosensor. also demonstrated simultaneous two biomarkers this With these attracted features, our immunoassay system shows promising applications in-field point-of-care test clinical diagnostics. (C) 2011 Elsevier B.V. All rights reserved.
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