Opposite effects of high- and low-frequency transcranial random noise stimulation probed with visual motion adaptation.

摘要: Transcranial random noise stimulation (tRNS) is a recent neuro-modulation technique whose effects at both behavioural and neural level are still debated. Here we employed the well-known phenomenon of motion after-effect (MAE) in order to investigate high- vs. low-frequency tRNS on adaptation recovery. Participants were asked estimate MAE duration following prolonged (20 s) complex moving pattern, while being stimulated with either sham or across different blocks. Different groups administered tRNS. Stimulation sites bilateral human MT (hMT+) frontal areas. The results showed that, whereas no induced by stimulating areas, when applied hMT+, high-frequency caused significant decrease corresponding increase duration. These findings indicate that have opposed adaptation-dependent unbalance between neurons tuned opposite directions, thus neuronal excitability.