摘要: Objective: To quantitatively associate iris color with melanocyte pigment content. Methods: Autopsy eyes were classified as uniform-blue, uniform-hazel, or uniform-brown showing a darker peripupillary ring. Using electron microscopic images and computerized image analysis, area, number, size of mature melanosomes within the perinuclear cytoplasmic area only peripheral areas superficial stromal melanocytes combined measured. Results: Average melanosomal per (AMAC) average number (AMNC) significantly differed across groups (overall P =.06 for AMAC =.07 AMNC). The was larger in central zone (within 1 mm around pupillary margin) than intermediate (between 2 ( =.002), but AMNC did not differ between zones. melanosome =.11). Conclusion: Differences colors are at least partially attributed to variable melanocytes.
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