Taurine supplementation has anti-atherogenic and anti-inflammatory effects before and after incremental exercise in heart failure.

摘要: Background:The purpose of this study was to examine the anti-atherogenic and anti-inflammatory effect supplemental taurine prior following incremental exercise in patients with heart failure (HF).Methods:Patients HF left ventricle ejection fraction less than 50%, placed functional class II or III according New York Heart Association classification, were randomly assigned two groups: (1) supplementation; (2) placebo. The group received oral (500 mg) 3 times a day for 2 weeks, performed before after supplementation period. placebo followed same protocol, but starch supplement rather taurine. multilevel treadmill test done using modified Bruce protocol.Results:Our results indicate that inflammatory indices [C-reactive protein (CRP), platelets] decreased pre-exercise, post-supplementation post-exercise, as compared pr...