Angiogenesis in bronchial asthma.

作者: Krzysztof Pałgan , Zbigniew Bartuzi

DOI: 10.1177/0394632015580907

关键词:

摘要: Bronchial asthma is a chronic inflammatory disease characterised by airflow obstruction that may be reversed spontaneously or in response to treatment. The airway inflammation can lead structural changes and remodelling consisting of subepithelial layer thickening, smooth muscle hyperplasia angiogenesis. Subepithelial hypervascularity angiogenesis the airways are part wall asthma. Increased vascularity bronchial mucosa closely related expression angiogenic factors like vascular endothelial growth factor (VEGF), angiopoietin hypoxia-inducible (HIF). scope present review summarise roles anagiogenic treatment development.

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