作者: Krzysztof Pałgan , Zbigniew Bartuzi
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摘要: Bronchial asthma is a chronic inflammatory disease characterised by airflow obstruction that may be reversed spontaneously or in response to treatment. The airway inflammation can lead structural changes and remodelling consisting of subepithelial layer thickening, smooth muscle hyperplasia angiogenesis. Subepithelial hypervascularity angiogenesis the airways are part wall asthma. Increased vascularity bronchial mucosa closely related expression angiogenic factors like vascular endothelial growth factor (VEGF), angiopoietin hypoxia-inducible (HIF). scope present review summarise roles anagiogenic treatment development.