Development of the Pulmonary Vasculature

摘要: Publisher Summary This chapter reviews current concepts related to the formation of vascular beds in normal lung at different stages growth and maturation, comments briefly on aberrant that results a still adequately functioning lung, summarizes vasculature aging. It also highlights presence signaling systems that, triggered by ambient oxygen tension, change density adult lung. The units form close coordination with airways alveoli. Lung is achieved expansion existing structures templates. As networks increase size three-dimensional complexity, accompanied regression unneeded until these are appropriate stage development. In this way, formed utero, postnatal period, early childhood, develop, enlarge remodeled. human embryo, starts onset organogenesis fourth week gestation. anlage develops from foregut, it vascularized ingrowth plexus derived heart main pulmonary artery migrating angioblasts. At 36 weeks term gestation, responds burst as continue expand diameter length, many new intra-acinar added gas-exchange surface. first months life, proximal vessels increases more than distal ones reflecting small developing periphery.