- Integrins, Cytoskeletal and Extracellular Matrix Proteins in Developing Smooth Muscle Cells of Human Aorta
作者： Marina A. Glukhova , Victor E. Koteliansky
DOI: 10.1016/B978-012632310-8/50004-8
关键词:
摘要: Publisher Summary This chapter illustrates the expression patterns of several cytoskeletal, contractile, extracellular matrix proteins, and integrins in smooth muscle cells developing, adult, atherosclerotic human aorta. intends to describe phenotypic properties during development disease states; characterize diversity vascular cells; analyze possible strategies for regulation individual gene used transitions role genetic (intrinsic) environmental (extrinsic) factors smooth-muscle-cell expression. Whereas intrinsic control plays a major early events differentiation, extrinsic probably serve as signals morphogenetic determine mature cells. focuses on analyzing coordinate changes components, laminin, fibronectin, receptors, integrins, cytoskeletal differentiation markers
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