作者: Romain Haudecoeur , Marine Peuchmaur , Basile Pérès , Maxime Rome , Germain Sotoing Taïwe
DOI: 10.1016/J.JEP.2017.10.011
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摘要: Abstract Ethnopharmacoalogical relevance The genus Nauclea in Africa comprises seven species. Among them, N. latifolia , diderrichii and pobeguinii are widely used by the local population traditional remedies. Preparation from various parts of plants (e.g. roots, bark, leaves) indicated healers for a wide range diseases including malaria, pain, digestive ailments or metabolic diseases. Materials methods A literature search was conducted on African species using scientific databases such as Google Scholar, Pubmed SciFinder. Every document ethnopharmacological, phytochemical pharmacological written English French were analyzed. Results discussion is ethnomedicine all along sub-Saharan Africa. Several populations consider major source remedies malaria. In this regard, two improved medicines currently under development extracts . Concerning chemical composition genus, indoloquinolizidines alkaloids could be considered class compounds they reported every analyzed species, with numerous structures identified. Based indications considerable amount studies to ensure activity attempt link them presence particular plant extracts. Conclusion Many experimental validate malaria pain). However, bioactive rarely identified therefore, there clear need further evaluations well toxicity experiments. sustainability these plants, especially threatened should kept mind adapt uses preparation modes