Amine-containing compound analysis methods
作者： Subhasish Purkayastha , Darryl Pappin , Subodh B. Nimkar , Scott Daniels
DOI:
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摘要: The present teachings provide methods for analyzing one or more amine-containing compounds in samples using isobaric labels and parent-daughter ion transition monitoring (PDITM). In various embodiments, the comprise steps of: (a) labeling with different tags from a set of tags, each tag comprising reporter portion; (b) combining at least portion isobarically labeled to produce combined sample; (c) subjecting sample PDITM; (d) measuring signal transmitted ions; (e) determining concentration based on comparison measured corresponding signals standard compound.
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