Chromium(III) as a Male Preconception Carcinogen in Mice

摘要: Numerous epidemiological studies have suggested significant correlation between paternal exposure to chemical carcinogens or radiation and incidence of childhood cancers, including brain tumor, Wilm’ tumor kidney, leukemia, hepatoblastoma, retinoblastoma sarcoma in soft tissues (Savitz Chen, 1990; Olsen et al., 1991; Bunin al, 1992; Tomatis, 1994). Interpretations some these data been controversial, particularly with regard effects. However, recently several very large smoking, conducted different parts the world, established associations preconception smoking levels risk cancer children, a high degree statistical significance (Sorahan 1997a b; Ji 1997). These results provide strong confirmation that carcinogenesis does occur humans.