Follow-up study after resection of intraductal papillary mucinous neoplasm of the pancreas; special references to the multifocal lesions and development of ductal carcinoma in the remnant pancreas.

作者: Takao Ohtsuka , Hiroshi Kono , Reiko Tanabe , Yosuke Nagayoshi , Yasuhisa Mori

DOI: 10.1016/J.AMJSURG.2011.04.007

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摘要: Abstract Background Frequency and characteristics of metachronous occurrence multifocal intraductal papillary mucinous neoplasms (IPMNs) or distinct pancreatic ductal adenocarcinomas (PDACs) in the remnant pancreas during follow-up evaluation after pancreatectomy for IPMNs have not been well known. The aim this study was to investigate outcomes resection IPMNs, especially focusing on PDACs. Methods Medical records 172 patients who underwent were reviewed retrospectively, data regarding PDACs a mean postoperative period 64 months collected. Results incidence including synchronous 20% (34 172), that 9.9% (17 172). Ten developed time 23 (range, 12–84 mo), 2 with main duct (both carcinoma situ) required pancreatectomy. Six 84 12–150 mo). Four them found tumor size less than cm, whereas remaining be unresectable more 10 years IPMNs. Conclusions Intense long-term is necessary early detection as malignant

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