Competitive Exclusion Principle in Ecology and Absolute Asymmetric Synthesis in Chemistry

摘要: The key concepts underlying the Frank model (1953) for spontaneous asymmetric synthesis in chemistry are traced back to pioneering works of Volterra (1926) and Lotka (1932) on biological species competition. Lotka-Volterra (L-V) two-species exclusive competition reduces special case distinguishable but degenerate (i.e., enantiomers). important ecological principle competitive exclusion, originally derived from L-V two-competitors model, is a consequence sufficiently antagonistic interactions between competing limited common resources, or mutual inhibition, as term known chemical literature absolute synthesis. models described by same general differential equations, nevertheless crucial thermodynamic distinction these necessary correlate selection selectivity arising 1) absence reversibility transformations, marked contrast reactions, 2) constraints scenarios reaction rate constants required fulfill micro-reversibility.