Octanorcucurbitane Triterpenoids Protect against tert-Butyl Hydroperoxide-Induced Hepatotoxicity from the Stems of Momordica charantia

作者: Chi-I Chang , Chiy-Rong Chen , Yun-Wen Liao , Wen-Ling Shih , Hsueh-Ling Cheng

DOI: 10.1248/CPB.58.225

关键词:

摘要: Four novel octanorcucurbitane triterpenes, octanorcucurbitacins A—D (1—4), together with one known triterpene, kuguacin M (5), were isolated from the methyl alcohol extract of stems Momordica charantia. Their structures elucidated on basis extensive spectroscopic analyses. Compound 3 inhibited tert-butyl hydroperoxide (t-BHP)-induced hepatotoxicity against HepG2 cells.

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