Models for Angiogenesis

摘要: The study of angiogenesis has produced a plethora creative assays through which various aspects vascular formation and growth are observed, measured, evaluated, inhibited. A basic theme investigation is that multiple models needed to prove hypothesis. Thus, different tested in separate order circumscribe those selected effects on the vasculature. Traditional have generally been categorized into either vitro or vivo assays. In allow for more strict control over local microenvironment, sometimes at expense authenticity event, whereas enable accurate observations simulated live environment optimizing certain variables. balance techniques involving both led better understanding overall process angiogenesis, thus enabled development effective targeting therapeutic agents. Keywords: tubules; endothelial cells; HUVEC; organic culture; implants; chamber assay