Plasma vitamin D and biomarkers of cardiometabolic disease risk in adult Canadians, 2007-2009.

摘要: INTRODUCTION Vitamin D may modulate cardiometabolic disease risk, although the relationship has not been investigated in general Canadian population. Understanding this inform public health strategies to curb incidence of Canada and elsewhere. The objectives study were examine association between vitamin traditional novel biomarkers describe extent month-to-month fluctuations METHODS We examined plasma 25-hydroxyvitamin a range risk participants (n = 1,928; age range, 16-79 years) from Health Measures Survey. conducted linear regressions analyses (adjusted for sex, waist circumference, physical activity, hormone use, season) assess dysglycemia, dyslipidemia, inflammation repeated stratified by we evaluated monthly men women. RESULTS observed wide variations D; more pronounced men. Plasma was inversely associated with insulin, insulin resistance, triglycerides, total cholesterol, low-density lipoprotein ratio high-density cholesterol but fasting glucose, apolipoprotein A1, B, C-reactive protein, fibrinogen, or homocysteine. This pattern varied CONCLUSION various metabolic processes influence Canadians. These findings have implications when recommending prevention related conditions.