The location of C2, C4, and BF relative to HLA-B and HLA-D.
作者： Donald D. Raum , Zuheir L. Awdeh , David Glass , Edmond Yunis , Chester A. Alper
DOI: 10.1007/BF01561689
关键词:
摘要: The loci forHLA-A, B, C, D, andDR are known to be closely linked the structural for complement components C2, BF, and duplicated C4, C4A C4B. Conflicting evidence has been presented order of these genes. However, new techniques have made possible identification markers in theHLA-D andC4 region nearly all identified haplotypes. In our population we confirmed fiveHLA-B-D crossovers each case informative allotypes or C4B segregated withHLA-D orDR suggesting that proteins lie close toHLA-D andDR. These findings may importance resolving problems encountered assignment ofHLA-D alleles.
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