Serum complement 'supergenes' of the major histocompatibility complex in man (complotypes).
作者： Chester A. Alper , Donald Raum , Sharon Karp , Zuheir L. Awdeh , Edmond J. Yunis
DOI: 10.1111/J.1423-0410.1983.TB04124.X
关键词:
摘要: The loci for the complement proteins C2 and BF, two C4 are closely linked to one another. In many hundreds of meioses no crossing over has been detected between these loci. addition, alleles four occur in specific combinations not predicted by their gene frequencies much same way as Rh MNS systems. These units termed complotypes. There 14 complotypes with excess 1% our study population normal sixth chromosomes from Caucasians. Since they also intimately associated HLA-DR, comploytypes may be importance screening programs transplantation.
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