Increased risk of depression in patients with rheumatoid arthritis: a seven-year population-based cohort study

摘要: OBJECTIVE: Rheumatoid arthritis (RA) is a costly and crippling autoimmune disease that can lead to the development of depression, contributing suboptimal clinical outcomes. However, no longitudinal studies have identified an association between rheumatoid subsequent depression. This study aimed investigate incidence risk factors depression among RA patients in Taiwan. METHODS: Using Taiwan's National Health Insurance Research Database, we 3,698 newly diagnosed aged 18 years or older, together with 7,396 subjects without matched by sex, age index date, 2000 2004. The cases were evaluated using Cox proportional-hazard regression. RESULTS: was 1.74-fold greater cohort than non-RA (11.80 versus 6.89 per 1,000 person-years; p<0.01). Multivariate analysis showed who female, had comorbidities such as stroke, chronic kidney disease, cancer significantly compared those these conditions. CONCLUSION: population-based strong relationship findings could be beneficial healthcare providers for identifying individuals higher predisposition thereby possibly facilitating provision appropriate rehabilitation intervention after onset support patient's adaptation.