The relation of CT-determined tumor parameters and local and regional outcome of tonsillar cancer after definitive radiation treatment.

作者: Robert Hermans , Katya Op de beeck , Walter Van den Bogaert , Alexis Rijnders , Lorenzo Staelens

DOI: 10.1016/S0360-3016(00)01559-5

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摘要: Abstract Purpose: To investigate the value of CT-derived tumor parameters as predictor local and regional outcome tonsillar squamous cell carcinoma treated by definitive radiation therapy. Methods Materials: The pretreatment CT studies 112 patients with were reviewed. After redigitizing films, primary nodal volume was calculated summation-of-areas technique. aspect graded using a 3-point scale (homogenous, inhomogeneous, necrotic). Mean follow-up time 33 months. Actuarial statistical analysis done for each covariates; multivariate performed Cox's proportional hazards model. Results: In actuarial analysis, CT-determined significantly correlated recurrence rate ( p = 0.1). T N categories independent predictors outcomes, respectively. Conclusion: Compared to other head-and-neck sites, have only marginal predictive regarding after therapy in cancer.

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