Molecular diagnosis of infections and resistance in veterinary and human parasites

摘要: Since 1977, >2000 research papers described attempts to detect, identify and/or quantify parasites, or disease organisms carried by ecto-parasites, using DNA-based tests and 148 reviews of the topic were published. Despite this, only a few for parasitic diseases are routinely available, most these optional used occasionally in diagnosis. Malaria, trypanosomiasis, toxoplasmosis, leishmaniasis cryptosporidiosis diagnosis may be assisted testing some countries, but there very cases where detection veterinary parasites is tests. The diagnoses bacterial (e.g. lyme disease) viral tick borne encephalitis) which transmitted ecto-parasites more commonly use tests, developing species makes up almost 20% literature. Other important uses epidemiological risk assessment, quality control food water, forensic parasite biology research. Some water-borne including Cryptosporidium Giardia, routine checks water treatment, food-testing applications have not been adopted practice. Biological research, widest diagnostics, delivering enhanced understanding guidelines managing diseases. limited uptake date, little doubt that they offer great potential also provide further information implementation strategies. For example, variant sequences within other can differentiated manner similar genetic medicine livestock breeding. If an association between DNA sequence phenotype has demonstrated, then qualities such as drug resistance, strain divergence, virulence, origin isolates could inferred No clinical commercial parasitology available organisms. Why had bigger impact human medicine? To explore this question, technological, biological, economic sociological factors must considered. Additionally, realistic expectation progress needed. enhance management many ways, patience, persistence dedication will needed achieve goal.