Non-invasive one-point carotid wave intensity in a large group of healthy subjects: A ventricular-arterial coupling parameter.

摘要: The analysis of wave intensity (WI) evaluates the working condition heart interacting with arterial system. WI in normal subjects has two peaks, first (W 1) reflects left ventricle (LV) contractile performance, second 2) is related to ability LV actively stop aortic blood flow. aim study was investigate reference values W 1 and 2 a group apparently healthy through radiofrequency-based 680 (388 men mean age 43.0 ± 17.4 years, range 16–92; 292 women 44.8 ± 17.7 years, 16–86) were enrolled underwent physical examination, pressure (BP) rate (HR) measurements comprehensive transthoracic echocardiogram performed. Measurement local obtained at level common carotid artery before bifurcation, using high definition echo-tracking (12.37 ± 6.89) × 103 (9.76 ± 4.8) × 103 mmHg m/s3, p < 0.0001; (3.21 ± 1.81) × 103 (2.98 ± 1.69) × 103 mmHg m/s3, p = ns women, respectively. cohort divided into 5 groups (ages 16–29; 30–39; 40–49; 50–59; >60) stratified by gender. After adjustment for height, systolic BP HR, decreased (p < 0.0001 p = 0.026 trend) while no relation found 2. Multivariable regression age, gender, BP, ejection fraction stroke volume indexed body surface are predicted HR E/A as measure diastolic function, Inter intra-observer variability feasibility satisfactory. We reported their clinical correlations peaks WI, non-invasive hemodynamic index assessing ventricular–arterial coupling large subjects.