Evaluating pediatric brain tumor cellularity with diffusion-tensor imaging.
作者： Karen M. Gauvain , Robert C. McKinstry , Pratik Mukherjee , Arie Perry , Jeffrey J. Neil
DOI: 10.2214/AJR.177.2.1770449
关键词:
摘要: OBJECTIVE. MR imaging of central nervous system (CNS) malignancies falls short a definitive evaluation. Tissue diagnosis remains the gold standard. Diffusion-tensor measures apparent diffusion coefficient and anisotropy water in tissue. The purpose this study was to test hypothesis that may improve evaluation newly diagnosed CNS neoplasms. We examined relationship between coefficient, anisotropy, tumor cellularity 12 pediatric patients.MATERIALS AND METHODS. On basis histopathologic evaluation, tumors case series were segregated into three types: low-grade gliomas, embryonal tumors, nonembryonal high-grade tumors. Mean values obtained from solid components each compared with cellularity, total cellular area, nuclear area derived biopsy material.RESULTS. coefficien...
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