On the evolutionary relationships of Drosophila melanogaster

摘要: The gene coding for alcohol dehydrogenase (Adh) in Drosophila melanogaster maps to 2:50.1 on chromosome arm 2L. It is expressed both larvae and adults, an abundant enzyme that plays a role the detoxification of primary secondary alcohols. In most abundantly fat body gut. We have recently shown [49] major Adh transcripts differ adult transcript being initiated from promotor several hundred pairs 5′ which larval initiated. However region “larval adult” mRNA are identical. discuss recent studies transcriptional organization compare structure this D. with other species Drosophila. entire its surrounds has been sequenced four [45,48]. This data used not only study phylogenetic relationships, but also types sequence variation seen between species. constraints mutational change, especially respect codons, will be discussed.