Early diagnosis of asymptomatic oral and oropharyngeal squamous cancers

摘要: An examination of the oral cavity and oropharynx in asymptomatic patients at high risk requires an orderly visual inspection entire oropharyngeal mucosa with particular attention to tongue, floor mouth, soft palate, uvula, tonsillar pillars, lingual aspects retromolar trigones. Completion clear documentation should be recorded. Detected lesions that do not resolve a reasonable length time--two three weeks--require intense assiduous investigation. The following specifics considered. 1. Alcohol drinkers cigarette smokers, especially those 40 years age older, are very for development upper aerodigestive tract lung squamous carcinomas. 2. ventrolateral palate complex high-risk sites within oropharynx. 3. Persistent mucosal erythroplasia rather than leukoplakia is earliest sign carcinoma. These regarded merely as precancerous changes. evidence indicates these considered invasive carcinoma or situ unless proven otherwise by biopsy. 4. Toluidine blue staining useful diagnostic adjunct, particularly method ruling out false-negative clinical impressions. It may also used rinse encompass after negative guide improve biopsy yields. 5. If cancer identified, evaluations larynx, hypopharynx, esophagus, lungs performed rule multiple primary cancers.(ABSTRACT TRUNCATED AT 250 WORDS)