The Effects of Neurocognitive Remediation on Executive Processing in Patients With Schizophrenia

摘要: Approaches to cognitive remediation have differed across studies. Most of the larger studies concentrated on group treatments designed without benefit recent laboratory-based The current study describes a randomized trial an intensive program involving individual daily sessions 1 hour for up 3 months. It targets executive functioning deficits (cognitive flexibility, working memory, and planning) that are known be problematic in people with schizophrenia. Procedural learning, as well principles errorless targeted reinforcement, massed practice, was basis intervention. compared alternative therapy (intensive occupational therapy) control some effects therapeutic contact. Some improvements cognition followed both therapies. A differential effect favor found tests flexibility memory subgroups. There trend those receiving atypical antipsychotic medication more from flexibility. Although there were no consistent changes symptoms or social between groups, if improvement tasks reached threshold then is evidence improved, even over short duration trial. In addition, differentially improved self-esteem. This supports view can reduce this reduction may affect outcome, at least term.