Immunogenicity of Corynebacterium pseudotuberculosis and the effect of adjuvants in mice.
作者： K.A. Brogden , R.C. Cutlip , H.D. Lehmkuhl
DOI: 10.1016/0021-9975(85)90003-9
关键词:
摘要: Abstract Intraperitoneal inoculation of CF1 mice with 100 μg, 200 or 300 μg whole cell (WC) 250 500 1000 wall (CW) Corynebacterium pseudotuberculosis induced varying degrees protection after intravenous challenge immunity 7·2 × 104 CFU C. pseudotuberculosis. Generally, the degree increased dose WC CW. However, intraperitoneal heat-killed Mycobacterium bovis BCG; 50 150 either muramyl dipeptide (MDP) trehalose dimycolate (TDM); 350 700 1400 parvum did not induce resistance to 7·4 The by CW was enhanced adding BCG, MDP, but in any adjuvants.
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