The proinflammatory transcription factor NFκB: a potential target for novel therapeutical strategies
作者： P. Renard , M. Raes
关键词:
摘要: NFκB is a ubiquitous transcription factor involved in the proinflammatory response to cytokines (such as IL-1 or TNF-α) and some particular stresses. The unraveling of molecular mechanisms its activation quite recent, particularly case IL-1-stimulated cells, but identification molecules this pathway opens new prospects both pharmacological toxicological research.
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