In Vivo Multiparametric Ultrasound Imaging of Structural and Functional Tumor Modifications during Therapy
作者： Alexandre Dizeux , Thomas Payen , Delphine Le Guillou-Buffello , Eva Comperat , Jean-Luc Gennisson
DOI: 10.1016/J.ULTRASMEDBIO.2017.03.021
关键词:
摘要: Longitudinal imaging techniques are needed that can meaningfully probe the tumor microenvironment and its spatial heterogeneity. Contrast-enhanced ultrasound, shear wave elastography quantitative ultrasound ultrasound-based provide information on vascular function micro-/macroscopic tissue structure. Modifications of induced by cytotoxic anti-angiogenic molecules in ectopic murine Lewis lung carcinoma tumors were monitored. The most heterogenous structures found treated with drug simultaneously accumulated highest levels necrosis fibrosis. group presented number correlations between parameters related to those micro-/macrostructure microenvironment. Results suggest how patterns multiparametric modifications be a more insightful marker changes occurring within during therapy.
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sci-hub.se 参考文章(42)
Roxana M. Vlad, Michael C. Kolios, Gregory J. Czarnota, Ultrasound imaging of apoptosis: spectroscopic detection of DNA-damage effects at high and low frequencies. Methods of Molecular Biology. ,vol. 682, pp. 165- 187 ,(2011) , 10.1007/978-1-60327-409-8_13
Ahmed El Kaffas, Ali Sadeghi-Naini, Omar Falou, William Tyler Tran, Stephanie Zhou, Amr Hashim, Jason Fernandes, Anoja Giles, Gregory J. Czarnota, Assessment of tumor response to radiation and vascular targeting therapy in mice using quantitative ultrasound spectroscopy Medical Physics. ,vol. 42, pp. 4965- 4973 ,(2015) , 10.1118/1.4926554
Gilda G. Hillman, Vinita Singh-Gupta, Hao Zhang, Areen K. Al-Bashir, Yashwanth Katkuri, Meng Li, Christopher K. Yunker, Amit D. Patel, Judith Abrams, E. Mark Haacke, Dynamic contrast-enhanced magnetic resonance imaging of vascular changes induced by sunitinib in papillary renal cell carcinoma xenograft tumors. Neoplasia. ,vol. 11, pp. 910- 920 ,(2009) , 10.1593/NEO.09618
Thomas Payen, Alexandre Dizeux, Capucine Baldini, Delphine Le Guillou-Buffello, Michele Lamuraglia, Eva Comperat, Olivier Lucidarme, S. Lori Bridal, VEGFR2-Targeted Contrast-Enhanced Ultrasound to Distinguish between Two Anti-Angiogenic Treatments Ultrasound in Medicine & Biology. ,vol. 41, pp. 2202- 2211 ,(2015) , 10.1016/J.ULTRASMEDBIO.2015.04.010
John M. Hudson, Ross Williams, Charles Tremblay-Darveau, Paul S. Sheeran, Laurent Milot, Georg A. Bjarnason, Peter N. Burns, Dynamic contrast enhanced ultrasound for therapy monitoring European Journal of Radiology. ,vol. 84, pp. 1650- 1657 ,(2015) , 10.1016/J.EJRAD.2015.05.013
Devrim Bozkurt, Banu Sarsik, Ender Hur, Muhittin Ertilav, Burcak Karaca, Ozge Timur, Selahattin Bicak, Fehmi Akcicek, Soner Duman, A novel angiogenesis inhibitor, sunitinib malate, in encapsulating peritoneal sclerosis Journal of Nephrology. ,vol. 24, pp. 359- 365 ,(2011) , 10.5301/JN.2011.6257
Edward Leen, Michalakis Averkiou, Marcel Arditi, Peter Burns, Daniela Bokor, Thomas Gauthier, Yuko Kono, Olivier Lucidarme, Dynamic contrast enhanced ultrasound assessment of the vascular effects of novel therapeutics in early stage trials European Radiology. ,vol. 22, pp. 1442- 1450 ,(2012) , 10.1007/S00330-011-2373-2
Guillaume Barrois, Alain Coron, Thomas Payen, Alexandre Dizeux, Lori Bridal, A multiplicative model for improving microvascular flow estimation in dynamic contrast-enhanced ultrasound (DCE-US): theory and experimental validation IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control. ,vol. 60, pp. 2284- 2294 ,(2013) , 10.1109/TUFFC.2013.6644733
Shingo Matsumoto, Keita Saito, Yoichi Takakusagi, Masayuki Matsuo, Jeeva P Munasinghe, Herman D Morris, Martin J Lizak, Hellmut Merkle, Keiji Yasukawa, Nallathamby Devasahayam, Sankaran Suburamanian, James B Mitchell, Murali C Krishna, None, In vivo imaging of tumor physiological, metabolic, and redox changes in response to the anti-angiogenic agent sunitinib: longitudinal assessment to identify transient vascular renormalization. Antioxidants & Redox Signaling. ,vol. 21, pp. 1145- 1155 ,(2014) , 10.1089/ARS.2013.5725
Thomas Payen, Alain Coron, Michele Lamuraglia, Delphine Le Guillou-Buffello, Emmanuel Gaud, Marcel Arditi, Olivier Lucidarme, S. Lori Bridal, Echo-Power Estimation from Log-Compressed Video Data in Dynamic Contrast-Enhanced Ultrasound Imaging Ultrasound in Medicine and Biology. ,vol. 39, pp. 1826- 1837 ,(2013) , 10.1016/J.ULTRASMEDBIO.2013.03.022