Dissociation of neuropeptide Y and somatostatin in Parkinson's disease
作者： J.M. Allen , A.J. Cross , T.J. Crow , F. Javoy-Agid , Y. Agid
DOI: 10.1016/0006-8993(85)91632-4
关键词:
摘要: Abstract The concentration of neuropeptide Y has been determined in the cortex and hippocampus subjects with Parkinson's disease compared to changes activity dopamine β-hydroxylase somatostatin. Despite a marked reduction somatostatin severely demented subject, both hippocampus, no significant change NPY was found either region. This finding therefore suggests that majority within is independent study provides some further evidence neurochemical similarities between dementia Alzheimer's disease.
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sci-hub.se 参考文章(25)
R. Bloom, R.G. Long, Radioimmunoassay of gut regulatory peptides Praeger,New York, NY. ,(1982)
G.K. Wilcock, M.M. Esiri, D.M. Bowen, C.C.T. Smith, Alzheimer's disease. Correlation of cortical choline acetyltransferase activity with the severity of dementia and histological abnormalities. Journal of the Neurological Sciences. ,vol. 57, pp. 407- 417 ,(1982) , 10.1016/0022-510X(82)90045-4
J.M. Allen, I.N. Ferrier, G.W. Roberts, A.J. Cross, T.E. Adrian, T.J. Crow, S.R. Bloom, Elevation of neuropeptide Y (NPY) in substantia innominata in Alzheimer's type dementia Journal of the Neurological Sciences. ,vol. 64, pp. 325- 331 ,(1984) , 10.1016/0022-510X(84)90180-1
A. J Cross, T. J Crow, E. K Perry, R. H Perry, G. Blessed, B. E Tomlinson, Reduced dopamine-beta-hydroxylase activity in Alzheimer's disease. BMJ. ,vol. 282, pp. 93- 94 ,(1981) , 10.1136/BMJ.282.6258.93
M.N. Rossor, P.C. Emson, C.Q. Mountjoy, Martin Roth, L.L. Iversen, Reduced amounts of immunoreactive somatostatin in the temporal cortex in senile dementia of Alzheimer type Neuroscience Letters. ,vol. 20, pp. 373- 377 ,(1980) , 10.1016/0304-3940(80)90177-9
D. Dawbarn, S.P. Hunt, P.C. Emson, Neuropeptide Y: regional distribution chromatographic characterization and immunohistochemical demonstration in post-mortem human brain. Brain Research. ,vol. 296, pp. 168- 173 ,(1984) , 10.1016/0006-8993(84)90526-2
Reijo J. Marttila, Urpo K. Rinne, Dementia in Parkinson's disease. Acta Neurologica Scandinavica. ,vol. 54, pp. 431- 441 ,(1976) , 10.1111/J.1600-0404.1976.TB04375.X
S. R. Vincent, O. Johansson, T. Hökfelt, B. Meyerson, C. Sachs, R. P. Elde, L. Terenius, J. Kimmel, Neuropeptide coexistence in human cortical neurones. Nature. ,vol. 298, pp. 65- 67 ,(1982) , 10.1038/298065A0
J.M. Allen, J.C. Yeats, T.E. Adrian, S.R. Bloom, Radioimmunoassay of neuropeptide Y. Regulatory Peptides. ,vol. 8, pp. 61- 70 ,(1984) , 10.1016/0167-0115(84)90029-6
DAVID M. BOWEN, CAROLYN B. SMITH, PAMELA WHITE, ALAN N. DAVISON, Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies. Brain. ,vol. 99, pp. 459- 496 ,(1976) , 10.1093/BRAIN/99.3.459