Not All Elderly People Benefit From Vitamin D Supplementation with Respect to Physical Function: Results From the Osteoporotic Fractures in Men Study, Hong Kong
作者： Ruth Chan , Dicken Chan , Jean Woo , Claes Ohlsson , Dan Mellström
DOI: 10.1111/J.1532-5415.2011.03789.X
关键词:
摘要: Objectives: To examine vitamin D status and its association with physical performance muscle mass in older Chinese men. Design: Cross-sectional prospective cohort study design. Setting: Hong Kong, People's of Republic China. Participants: Nine hundred thirty-nine community-dwelling men aged 65 for cross-sectional analysis 714 longitudinal analysis. Measurements: Baseline serum 25-hydroxyvitamin (25OHD) was measured using a competitive radioimmunoassay kit. 4-year measures (grip strength, 6-m walking speed, step length walk, time to complete five chair stands) were measured, appendicular skeletal (ASM) assessed dual-energy X-ray absorptiometry. Data collected confounding factors: demographic, number diseases, smoking, alcohol use, body index, activity, diet, season blood sampling, parathyroid hormone (PTH) level. Multivariate regression analyses performed adjustments factors. Results: Mean ± standard deviation 25OHD level this sample who had high baseline function 77.9 20.5 nmol/L; 94.1% participants levels 50 nmol/L or greater. Median (interquartile range) PTH 4.1 pmol/L (3.1�5.5 pmol/L). After adjustment potential factors, not associated change ASM. Conclusion: In are replete have function, may an important role mass.
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